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This is the theoretical basis for endogenously supplied gamma-glutamylcysteines ability to raise GSH levels, as being the product of the GCL enzyme, it can be taken up by cells intact, where it feeds directly into glutathione synthase to be converted to glutathione, effectively bypassing the dysfunctional GCL

A similar conversion from compound 1 to compound 2 was observed after the second illumination cycle and a conversion to compound 1 was observed after the addition of enzymes

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Moreover, the discovery challenges traditional views of CysLT-mediated inflammation and may help explain the effectiveness of current therapies that target these pathways